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SynFlup

The Synthesis Fluidic Platform “SynFluP” is dedicated to Organic Synthesis in Continuous Reactor

available to anyone through collaboration or service, or just for quick test !

 Better process safety

by lowering down

reactor dimensions

even for larger scale !

COLD

-80°C

REAGENT

compatible with

most reagents

Photo

Chemistry

1 flow equipement

SAFETY

unstable reagent

explosive, CMR

MICROMIXER

4 Small micromixers

1 large scale mixer

SUSPENSION

Fine suspension

Pd/C, NaBH4

 Better mixing

using specially designed micromixers, from 100µL/min to 10mL/min

Fine suspension are 

tolerated

Heterogeneous catalyst

from 500mg to 30g

GREEN

Less reagents

Less energy

Kinetics

from 5 ms

to 1h 

GAS/LIQUID

Hydrogen, oxygen

carbon dioxide

Temperature range :

-80°C to 250°C

Pressure range:

1 bar to 200 bar

Most reagents and solvent are compatibles :

bases, acids, hydrides, Grignards, OrganoLithium, Lewis acids, ...

Activation using non classical conditions :

photochemistry, photocatalysis

supercritiacl fluids (water, CO2, DMC) 

Greener process by

lowering down energy

usage, reagent excess and

fewer by-products

HEAT

up to 250°C

Amenable to ultrafast reactions (sub second)

to slower ones

(one hour max)

SOLVENT

almost no solvent limitation

Possible addition of

gas (H2, CO2, O2)

with tube in tube

or mass flow controler

SUPER

CRITICAL

Jasco System

2 reagents / gas

Description of Equipment

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Uniqsis FlowSyn

FlowSyn combines all the benefits of the FlowSyn system to deliver a compact, fully integrated, easy-to-use continuous flow reactor for single reactions. FlowSyn’s high resolution user interface quickly guides you through the process for setting up a flow chemistry reaction with two reagents. Once set up, FlowSyn automatically runs the experiment unattended, ensuring that critical parameters remain within defined limits.The system can easily be reconfigured for a variety of experiments. Carry out superheated reactions up to +150°C and small scale cooled reactions down to -78°C

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Vapourtec R4-R2+ unit

This unit provides the basic entities to preform reaction test with flexible HPLC pumps with ceramic heads inerted with PTFE and capable of handling strong acids such as HNO3. The coiled reactor is made in fluoropolymers and can be heated through the system from Room Temperature to 120°C, depending on required pressure. Additionally a module for heterogeneous reactions is available with columns of various capacities (from 7mL up to 50mL) able to work under the same temperature conditions. The pressure in the system is limited by the fittings at 30bar.

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Vapourtec V-3 Easy Scholar Unit 

This unit provides an advanced entry in unsafe reagents handling. The peristaltic pumps have very little pulsation and are able to handle slurries, strong oxidant and reducing agents. The digital command enables a quick and handy management of pumps, valve and collection. The reaction temperature can be fixed between Room Temperature and 120°C. Reaction pressure is limited by the capacities of peristaltic pumps at 10bar.

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